
PMDD stands for premenstrual dysphoric disorder. This should not be confused with Premenstrual Syndrome, or PMS. PMS refers to mood changes during certain periods of the menstrual cycle. It affects 80% of women. It can cause mood swings that range from mild to moderate. Some women may only feel a little moody one week before their period.
PMDD is the most severe form of PMS. It is almost like being turned into a werewolf by the full moon rising. It can be quite extreme for some people. It affects between 3% and 8% of women. It’s not as common than PMS.
PMDD can be treated with hormone therapy or antidepressants. I explain why PMDD can occur in women and the benefits of antidepressants. I explain the differences between continuous and intermittent antidepressant dosing. I also cover the main hormone treatments.
Lifestyle changes are an option if you don’t want to take any medication. Diet modifications include reducing sodium, eliminating sugar and nicotine, and changing your diet. This would be combined with getting regular exercise, such as 3-5 days a week, and sleeping for 7-9 hours each night.
A few nutritional supplements have been shown to be beneficial. These would be Calcium 1200mg/day, Vitamin B6 50-100mg/day. Other supplements would be Magnesium 200 – 360mg/day, Vitamin E 400 IU/day.
Studies have shown that some herbs can be beneficial.
Agnus castus extract is also known as Gingko biloba and Chasteberry.
Download the mood diary here:
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References:
Article about how SSRI’s increase allopregnalone
Griffin LD, Mellon SH. Selective serotonin-reuptake inhibitors directly alter the activity of neurosteroidogenic enzymes. Proc Natl Acad Sci U S A. 1999;96(23): 13512-13517.
Backstrom T, Bixo M, et. al. Allopregnanolone, mood disorders and allopregnanolone Prog Neurobiol. 2014 Feb; 113: 88-94. Epub 2013 Aug 23.
Schmidt PJ, Schiller CE, Rubinow D. Allopregnanolone: A mediator of affective switching in reproductive-moment disorders. Psychopharmacology (Berl). 2014;231(17): 3557-3567. doi: 10. 1007/s00213-014-3599-x
Griffin LD, Mellon SH. Selective serotonin-reuptake inhibitors directly alter the activity of neurosteroidogenic enzymes. Proc Natl Acad Sci U S A. 1999;96(23): 13512-13517.
Khine K. Rosenstein DL. Elin RJ. Niemela JE. Schmidt PJ. Rubinow DR. Magnesium retention and mood effects following intravenous Mg Infusion in Premenstrual Dysphoric Disorder. Biol Psychiatry. 2006 Feb 15;59(4): 327-33.
Yonkers KA. Pearlstein TB. Gotman N. Pilot study to evaluate fluoxetine, calcium and placebo for premenstrual syndrome. J Clin Psychopharmacol. 2013 Oct; 33(5): 614-20.
Disclaimer: The information contained on this channel is intended for education purposes only and does not constitute specific/personal medical advice. The videos and the answers to questions/comments do not create a doctor-patient relationship. These videos may be helpful for you if you are a patient of your own doctor.
https://medbusiness.net/if-you-suffer-from-premenstrual-dysphoria-watch-this/
Hey yall,
Here's my update of my 18th week on Vyvanse for the treatment of my Binge Eating Disorder.
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xo
Nic
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