What? What is a Cough Medicine for Depression?

Serotonin antidepressants, step aside there’s a new kid in town. FDA approved a new antidepressant containing the active ingredient in over-the counter cough medicine. The new antidepressant will be available in the near future and is expected to work faster than current antidepressants. This may be something you should ask your doctor if you are suffering from depression.

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References
Zorumski, Charles F et al. “Treatment-Resistant Minor Depression: Rationale to NMDA Receptors As Targets and Nitrous Oxide Therapy.” Frontiers of psychiatry vol. 6 172. 9 Dec. 2015, doi: 10.3389/fpsyt.2015. 00172

Chandrasekar, Raman. “Alcohol & NMDA receptor: Current research and future direction.” Frontiers of molecular neuroscience vol. 6 14. 28 May. 2013, doi: 10.3389/fnmol.2013. 00014

Bai G, Hoffman PW. Transcriptional Regulation and Expression of NMDA Receptors. In: Van Dongen AM, editor. Biology of the NMDA receptor. Boca Raton (FL): CRC Press/Taylor & Francis; 2009. Chapter 5.

Mutschler, Jochen et al. “Dextromethorphan withdrawal and dependence syndrome.” Deutsches Arzteblatt international vol. 107,30 (2010): 537-40. doi: 10.3238/arztebl.2010. 0537

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ADHD Medications
Two types of Stimulants
Methylphenidate (Concerta, Ritalin, Metadate, Methylin, Focalin) type Stimulant
Amphetamine Salts (Adderall, Vyvanse, Dexedrine, Dextrostrat) type Stimulants

Non Stimulant Drugs
Strattera (Atomoxetine) - A NRI - it affects the norepinephrine and dopamine levels between the brain synapses
Alpha 2 Agonists drugs Intuniv (Guanfacine) and Kapvay (Clonidine) these drugs are anti-hypertensive drugs (blood pressure meds) that trigger a neurotransmitter receptor called the Alpha 2 receptor (Alpha 2 receptor can be triggered by norepinephrine

The Five Delivery Mechanisms (The Five Ps)
Pill
Pump
Pellet
Patch
Pro Drug

Note there are other meds that are used OFF LABEL for ADHD. The meds listed above are the first line treatments, and you only use the off label meds if the person can't tolerate the side effects of the primary meds, or if they do not work for some reason.

TALK TO YOUR DOCTOR!!!


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